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Elicio Reports Complete Responses in KRAS PDAC Patients

Elicio Therapeutics reports complete responses in KRAS-driven PDAC patients following checkpoint inhibition, signaling potential for its ELI-002 7P vaccine candidate.GlobeNewswire

Meanwhile, academic research highlights the efficacy of personalized neoantigen vaccines in HNSCC and introduces TCRDiff, a generative diffusion model for designing antigen-specific T-cell receptors.newsbioRxiv

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AI / Methods2 days agoNew

Generative design of antigen-specific T-cell receptor sequences with a conditional diffusion model

T cell receptor (TCR)-based immunotherapy holds immense potential for treating cancers, autoimmunity, and infectious diseases, where antigen-specific TCR recognition is crucial for adaptive immune responses. Engineering or de novo generation of the complementarity-determining reg…

biorxiv · 2 days ago · Zhang, Y.; Liang, W.; Xu, S.; Witney, M.; Su, X.; Andrews, M. C.; Rossjohn, J.; Purcell, A

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Relevant work from earlier we're still surfacing — not today's news.