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NCT03988283 — Washington University School of Medicine neoantigen vaccine trial

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

TrackingPhase 1RecruitingRegistry updated 7 May 2026
Phase 1phaseRecruitingregistry status7enrollment2029-03-31primary completion

Registry IDNCT03988283
Lead sponsorWashington University School of Medicine
CollaboratorsChildren's Discovery Institute
PhasePhase 1
StatusRecruiting
IndicationPediatric Recurrent Central Nervous System Tumors
Enrollment7 participants (target)
Start date2024-10-02
Primary completion2029-03-31 (est.)
Last registry update7 May 2026

Every field above is mirrored from the study record on ClinicalTrials.gov (NCT03988283), which the sponsor maintains and which carries the full protocol summary, eligibility criteria, sites and contacts. No neoantigen vaccine is approved anywhere yet — every program here is investigational, and inclusion is not an endorsement. See the methodology for how the tracker is built.

Daily coverage of the modality, tumor type and players this study touches:

What phase is NCT03988283?

NCT03988283 (Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors) is registered on ClinicalTrials.gov as Phase 1, sponsored by Washington University School of Medicine.

Is NCT03988283 recruiting?

As of the 2026-05-07 registry update, NCT03988283 is listed as "Recruiting". Eligibility criteria, study sites and contacts are maintained by the sponsor on the ClinicalTrials.gov record.

Who is running NCT03988283?

The lead sponsor is Washington University School of Medicine. Collaborators: Children's Discovery Institute.

What condition does NCT03988283 study?

The registered condition is Pediatric Recurrent Central Nervous System Tumors. Primary completion is listed as 2029-03-31 (estimated).

Are results available for NCT03988283?

neoag.ai mirrors the registry's factual fields — sponsor, phase, status and dates — and does not publish trial results. Any posted results, publications, or outcome measures appear on the ClinicalTrials.gov record for NCT03988283.

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