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NCT03604978 — National Cancer Institute (NCI) cancer immunotherapy trial

Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma

TrackingPhase 1/2Active Not RecruitingRegistry updated 31 Jul 2026
Phase 1/2phaseActive Not Recruitingregistry status38enrollment2027-03-19primary completion

Registry IDNCT03604978
Lead sponsorNational Cancer Institute (NCI)
Collaborators
PhasePhase 1/2
StatusActive Not Recruiting
IndicationGrade 2 Meningioma, Grade 3 Meningioma, Recurrent Meningioma
Enrollment38 participants (target)
Start date2019-06-17
Primary completion2027-03-19 (est.)
Last registry update31 Jul 2026

Every field above is mirrored from the study record on ClinicalTrials.gov (NCT03604978), which the sponsor maintains and which carries the full protocol summary, eligibility criteria, sites and contacts. No neoantigen vaccine is approved anywhere yet — every program here is investigational, and inclusion is not an endorsement. See the methodology for how the tracker is built.

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What phase is NCT03604978?

NCT03604978 (Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma) is registered on ClinicalTrials.gov as Phase 1/2, sponsored by National Cancer Institute (NCI).

Is NCT03604978 recruiting?

As of the 2026-07-31 registry update, NCT03604978 is listed as "Active Not Recruiting". Eligibility criteria, study sites and contacts are maintained by the sponsor on the ClinicalTrials.gov record.

Who is running NCT03604978?

The lead sponsor is National Cancer Institute (NCI).

What condition does NCT03604978 study?

The registered conditions are Grade 2 Meningioma, Grade 3 Meningioma, Recurrent Meningioma. Primary completion is listed as 2027-03-19 (estimated).

Are results available for NCT03604978?

neoag.ai mirrors the registry's factual fields — sponsor, phase, status and dates — and does not publish trial results. Any posted results, publications, or outcome measures appear on the ClinicalTrials.gov record for NCT03604978.

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