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NCT06904066 — National Cancer Institute (NCI) neoantigen vaccine trial

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

TrackingPhase 1RecruitingRegistry updated 4 Sept 2026
Phase 1phaseRecruitingregistry status86enrollment2029-04-30primary completion

Registry IDNCT06904066
Lead sponsorNational Cancer Institute (NCI)
Collaborators
PhasePhase 1
StatusRecruiting
IndicationMalignancy, Hematologic, Neoplasms, Hematologic, Neoplasms, Hematopoietic, Blood Cancer, Hematological Neoplasms, Hematopoietic Malignancies, Dysmyelopoietic Syndromes, Hematopoetic Myelodysplasia, Myeloid Leukemia, Acute, Nonlymphoblastic Leukemia, Acute, Leukemia, Lymphocytic, Acute
Enrollment86 participants (target)
Start date2026-09-09
Primary completion2029-04-30 (est.)
Last registry update4 Sept 2026

Every field above is mirrored from the study record on ClinicalTrials.gov (NCT06904066), which the sponsor maintains and which carries the full protocol summary, eligibility criteria, sites and contacts. No neoantigen vaccine is approved anywhere yet — every program here is investigational, and inclusion is not an endorsement. See the methodology for how the tracker is built.

Daily coverage of the modality, tumor type and players this study touches:

What phase is NCT06904066?

NCT06904066 (Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies) is registered on ClinicalTrials.gov as Phase 1, sponsored by National Cancer Institute (NCI).

Is NCT06904066 recruiting?

As of the 2026-09-04 registry update, NCT06904066 is listed as "Recruiting". Eligibility criteria, study sites and contacts are maintained by the sponsor on the ClinicalTrials.gov record.

Who is running NCT06904066?

The lead sponsor is National Cancer Institute (NCI).

What condition does NCT06904066 study?

The registered conditions are Malignancy, Hematologic, Neoplasms, Hematologic, Neoplasms, Hematopoietic, Blood Cancer, Hematological Neoplasms, Hematopoietic Malignancies, Dysmyelopoietic Syndromes, Hematopoetic Myelodysplasia, Myeloid Leukemia, Acute, Nonlymphoblastic Leukemia, Acute, Leukemia, Lymphocytic, Acute. Primary completion is listed as 2029-04-30 (estimated).

Are results available for NCT06904066?

neoag.ai mirrors the registry's factual fields — sponsor, phase, status and dates — and does not publish trial results. Any posted results, publications, or outcome measures appear on the ClinicalTrials.gov record for NCT06904066.

Back to the full neoantigen vaccine trial tracker 107 studies, refreshed daily from ClinicalTrials.gov. Background: primer, glossary, and the companies landscape.