NCT06077760 — intismeran autogene (mRNA-4157) neoantigen vaccine trial
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Intismeran autogene (mRNA-4157 / V940), Moderna + Merck — INTerpath NSCLC, Phase 3
Registry record
| Registry ID | NCT06077760 ↗ |
|---|---|
| Lead sponsor | Merck Sharp & Dohme LLC |
| Collaborators | ModernaTX, Inc. |
| Phase | Phase 3 |
| Status | Recruiting |
| Indication | Non-small Cell Lung Cancer |
| Enrollment | 868 participants (target) |
| Start date | 2023-12-06 |
| Primary completion | 2030-06-25 (est.) |
| Last registry update | 21 Aug 2026 |
Every field above is mirrored from the study record on ClinicalTrials.gov (NCT06077760), which the sponsor maintains and which carries the full protocol summary, eligibility criteria, sites and contacts. No neoantigen vaccine is approved anywhere yet — every program here is investigational, and inclusion is not an endorsement. See the methodology for how the tracker is built.
Where this fits
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FAQ
What phase is NCT06077760?
NCT06077760 (A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)) is registered on ClinicalTrials.gov as Phase 3, sponsored by Merck Sharp & Dohme LLC.
Is NCT06077760 recruiting?
As of the 2026-08-21 registry update, NCT06077760 is listed as "Recruiting". Eligibility criteria, study sites and contacts are maintained by the sponsor on the ClinicalTrials.gov record.
Who is running NCT06077760?
The lead sponsor is Merck Sharp & Dohme LLC. Collaborators: ModernaTX, Inc..
What condition does NCT06077760 study?
The registered condition is Non-small Cell Lung Cancer. Primary completion is listed as 2030-06-25 (estimated).
Are results available for NCT06077760?
neoag.ai mirrors the registry's factual fields — sponsor, phase, status and dates — and does not publish trial results. Any posted results, publications, or outcome measures appear on the ClinicalTrials.gov record for NCT06077760.
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