Neoantigen × AI
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NEC / NEC OncoImmunity

NEC — applies its AI neoantigen-prediction platform to personalized vaccines (NECVAX-NEO1) and powers partners' pipelines.

Topic4 items2026-05-29 – 2026-06-15
02
Clinical

Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Neoadjuvant Triple-negative Breast Cancer

NEC Bio B.V. is conducting a Phase I/II trial of NECVAX-NEO1, a personalized neoantigen-targeting vaccine in neoadjuvant triple-negative breast cancer. The study evaluates the vaccine's combination with standard-of-care chemotherapy and anti-PD-1 therapy, with potential post-surgical extension to assess immune response and clinical outcomes in early-stage disease.

clinicaltrials · brief 2026-06-08 · published 2026-05-26
03
Clinical

Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Anti-PD-1/PD-L1 Therapy in Patients With Solid Tumors

NEC Bio B.V. is conducting a Phase I/II multicenter trial of NECVAX-NEO1 combined with PD-1/PD-L1 monoclonal antibodies in solid tumors. The study stratifies patients by response to prior checkpoint inhibitor therapy (Stable Disease/Partial Response vs. Progressive Disease), testing the vaccine's ability to rescue or sustain response in advanced settings.

clinicaltrials · brief 2026-06-04 · published 2026-01-08